Understanding Menopausal Hormone Therapy (MHT)

October 27, 2025
Blurry first-person view of a person in a plaid shirt typing on a laptop with a coffee cup nearby on a wooden desk

Menopause is a natural life stage, not a disease. But when symptoms start affecting your quality of life, like hot flashes, night sweats, vaginal dryness, brain fog, or sleep changes, relief and balance are possible.

That’s where Menopausal Hormone Therapy (MHT) comes in. There are two main types:

  • Local hormone therapy (targets one area)
  • Systemic hormone therapy (supports your whole body)

Let’s walk through what each does, how it works, and what to consider when talking to your provider.


Local Hormone Therapy: 

Local therapy works directly where it’s applied, usually in the vagina or surrounding tissues. It helps with Genitourinary Syndrome of Menopause (often called GSM). GSM can cause dryness, discomfort, pain with sex, or urinary symptoms like urgency and frequent infections. Because local therapy acts mostly in the tissues it’s applied to, only a tiny amount reaches the bloodstream. That means it’s considered safe for most people, even those who cannot take systemic hormones.

Common options in Canada include:

  • Estring vaginal ring
  • Vagifem vaginal tablet (estradiol)
  • Estragyn or Premarin vaginal cream
  • Intrarosa vaginal tablet (DHEA)
  • Osphena oral tablet (ospemifene), which acts like estrogen in vaginal tissues

U.S. equivalents include: ...

Want to keep reading?

Only myStoria members can read the rest of this article. It's free to join with the myStoria app!
Download on the App StoreGet It On Google Play
Already a member?
Click here to open this article in the myStoria community.
About the Author

Carly Malo is myStoria's Head of Concierge. She has 2 decades of experience in direct nursing care, having worked in long-term care, sports medicine, practical nursing, and fertility/reproductive health.

myStoria app icon
Stop holding it all in your head.
Download on the App StoreGet It On Google Play
Medical app screen showing a timeline of health story points including appointments, test results, nurse check-in, and diagnosis with dates from December 2025 to February 2026.