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May 25, 2026
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If you experience a pregnancy loss, you may have the option to have the pregnancy tissue tested to help understand why the miscarriage happened. This is sometimes called "POC testing" (products of conception testing) or simply "miscarriage tissue testing."
The test looks at the chromosomes, the structures in our cells that carry genetic information, to see if there was an abnormality that caused the pregnancy to stop developing.
Knowing whether this was the reason for your loss can provide answers during an incredibly difficult time and help guide decisions about future pregnancies.
The test looks for chromosome problems that may have caused the pregnancy to stop developing. The most common finding is when the pregnancy had the wrong number of chromosomes, either extra or missing. This includes conditions like Down syndrome and Trisomy 18, as well as situations where an entire chromosome is missing.
The test can also detect:
Chromosome abnormalities cause about 58% of all miscarriages (source), so this testing can provide answers for many people experiencing loss.
What if testing shows everything was normal?
If the test shows the pregnancy had normal chromosomes, your healthcare provider may want to look more closely at other possible causes like the shape of your uterus, hormone levels, or immune factors. When results come back normal, about 80% of couples...
Carly Malo is myStoria's Head of Concierge. She has 2 decades of experience in direct nursing care, having worked in long-term care, sports medicine, practical nursing, and fertility/reproductive health.
